Limitation of Regular Autosomal STR Testing for Paternity within an Isolated Population

The genetic testing for paternity is based on autosomal short tandem repeat (STR) markers, and the genetic relatedness is statistically presented. However, when the typical testing does not guarantee the paternal relationship, additional genetic analysis can be introduced to improve the result. Generally, additional STR typing with increased number of markers is performed to increase the power of discrimination, or paternal and maternal lineage testing is utilized to prove the relationship indirectly. However, these methods may not be suitable when it is difficult to test with additional STR markers, such as the samples from old body remains or when the test for maternal and paternal lineage does not provide significant information. Recent studies show that single nucleotide polymorphism (SNP) markers are also utilized as a complementary tool for paternity